KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MTBP
All Species:
13.33
Human Site:
Y745
Identified Species:
29.33
UniProt:
Q96DY7
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96DY7
NP_071328.2
904
102193
Y745
S
K
D
L
N
C
L
Y
P
R
K
R
L
V
K
Chimpanzee
Pan troglodytes
XP_001144500
904
102150
Y745
S
K
D
L
N
C
L
Y
P
R
K
R
L
V
K
Rhesus Macaque
Macaca mulatta
XP_001098134
904
101977
Y745
S
K
D
L
N
C
L
Y
P
R
K
R
L
V
K
Dog
Lupus familis
XP_851376
899
100550
Y740
S
K
D
V
N
C
L
Y
P
P
K
R
L
V
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BJS8
894
100296
P735
L
K
R
R
S
K
D
P
S
C
L
Y
P
Q
K
Rat
Rattus norvegicus
NP_001124189
894
100344
A735
L
K
R
R
S
K
D
A
S
C
L
Y
P
Q
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521539
320
36173
I163
G
R
A
M
I
D
V
I
L
Q
S
S
E
N
D
Chicken
Gallus gallus
XP_418460
855
95673
C698
S
K
D
L
D
C
F
C
P
K
K
R
L
M
K
Frog
Xenopus laevis
Q6NRW0
860
96289
K703
L
R
L
K
R
R
S
K
D
I
E
G
L
Y
P
Zebra Danio
Brachydanio rerio
XP_699763
774
86773
A617
G
S
V
P
D
G
E
A
L
H
S
E
P
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001189302
511
56225
V354
R
P
K
R
S
T
P
V
K
S
T
K
P
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
97.4
87
N.A.
77.3
77.2
N.A.
22
57.7
51.1
41.8
N.A.
N.A.
N.A.
N.A.
21.6
Protein Similarity:
100
99.3
98.7
91.9
N.A.
85.5
85.7
N.A.
28.4
72.4
68.2
57.1
N.A.
N.A.
N.A.
N.A.
32.9
P-Site Identity:
100
100
100
86.6
N.A.
13.3
13.3
N.A.
0
66.6
6.6
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
93.3
N.A.
20
20
N.A.
26.6
86.6
20
13.3
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
19
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
46
0
10
0
19
0
0
0
0
0
% C
% Asp:
0
0
46
0
19
10
19
0
10
0
0
0
0
0
10
% D
% Glu:
0
0
0
0
0
0
10
0
0
0
10
10
10
10
10
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
19
0
0
0
0
10
0
0
0
0
0
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
10
0
10
0
0
0
0
0
% I
% Lys:
0
64
10
10
0
19
0
10
10
10
46
10
0
0
64
% K
% Leu:
28
0
10
37
0
0
37
0
19
0
19
0
55
0
0
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
37
0
0
0
0
0
0
0
0
10
0
% N
% Pro:
0
10
0
10
0
0
10
10
46
10
0
0
37
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
0
0
0
19
0
% Q
% Arg:
10
19
19
28
10
10
0
0
0
28
0
46
0
0
10
% R
% Ser:
46
10
0
0
28
0
10
0
19
10
19
10
0
10
0
% S
% Thr:
0
0
0
0
0
10
0
0
0
0
10
0
0
0
0
% T
% Val:
0
0
10
10
0
0
10
10
0
0
0
0
0
37
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
37
0
0
0
19
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _